Bulk Anti-Human CD64 (10.1) Antibody

Product Specifications

Background

Fc gamma receptors (FcγRs) are membrane-bound proteins which control and mediate communication of IgG antibodies within the immune system. These receptors play a crucial role in the link between the innate and adaptive immune system. FcγRI, CD64, is expressed on dendritic cells, macrophages/monocytes, and granulocytes. Of the FcγRs, FcγRI is capable of interacting with monomeric IgG with relatively high affinity.

Product Name Alternative

Fc-gamma receptor 1, FcγRI, Fc Gamma Receptor Ia, Fc-Gamma RIA, CD64

UniProt

P12314

Host

Mouse

Reactivity

Human

Immunogen

Rheumatoid synovial fluid cells and fibronectin purified human monocytes

Target

CD64

Isotype

IgG1 κ

Clone

10.1

Applications

Blocking, Functional Assays, Flow Cytometry, Immunofluorescence, IHC (Frozen), Immunoprecipitation

Purification Method

This monoclonal antibody was purified using Protein A

Concentration

>2.0 mg/mL

Endotoxin

≤ 1.0 EU/mg as determined by the LAL method

Purity

>95% by SDS-PAGE and HPLC

Buffer

ICH3001-100ml ICH3002-100ml ICH3003-100ml

Shipping Conditions

Blue ice

Storage Conditions

This antibody is stable for at least one week when stored sterile at 2-8°C. For long term storage aseptically aliquot in working volumes without diluting and store at –80°C. Avoid Repeated Freeze Thaw Cycles.

Specificity

Clone 10.1 recognizes an epitope on human FcγRI

Formulation

This monoclonal antibody is aseptically packaged and formulated in 0.01 M phosphate buffered saline (PBS) pH 7.2 – 7.4, 150 mM NaCl with no carrier protein, potassium or preservatives added. BSA and azide free