Anti-Mouse IFN Gamma (H22) In Vivo Antibody - Low Endotoxin

Product Specifications

Background

Interferon-gamma (IFN-gamma) or type II interferon is a dimerized soluble cytokine that is the only member of the type II class of interferons.1 It is a cytokine critical for innate and adaptive immunity against viral and intracellular bacterial infections and for tumor control. IFNG is produced predominantly by natural killer (NK) and natural killer T (NKT) cells as part of the innate immune response, and by CD4 and CD8 cytotoxic T lymphocyte (CTL) effector T cells once antigen-specific immunity develops.2 IFN-gamma has antiviral, immunoregulatory, and anti-tumour properties

Product Name Alternative

Interferon gamma, Ifng

UniProt

P01580

Host

Armenian Hamster

Reactivity

Mouse

Immunogen

Purified Recombinant Mouse IFN-gamma (>98%)

Target

IFN gamma

Isotype

IgG

Clone

H22

Applications

Immunoprecipitation, Western Blot, Neutralization, ELISA, Immunofluorescence

Purification Method

This monoclonal antibody was purified using Protein A

Concentration

1.0 mg/mL

Endotoxin

<1.0 EU/mg as determined by the LAL method

Purity

>95% by SDS-PAGE and HPLC

Buffer

ICH3001-100ml ICH3002-100ml ICH3003-100ml

Shipping Conditions

Blue ice

Storage Conditions

Anti-IFN gamma In Vivo Antibody - Low Endotoxin (H22) is stable for at least one week when stored sterile at 2-8°C. For long term storage aseptically aliquot in working volumes without diluting and store at –20°C in a manual defrost freezer. Avoid Repeated Freeze Thaw Cycles.

Related Products

Anti-IFN gamma In Vivo Antibody - Ultra Low Endotoxin [H22] (ICH1109UL)

Specificity

Anti-IFN gamma In Vivo Antibody - Low Endotoxin (H22) recognizes an epitope on Mouse IFN-gamma

Formulation

0.01 M phosphate buffered saline (PBS) pH 7.2, 150 mM NaCl with no carrier protein, potassium or preservatives added.

Aggregation

Aggregation level ≤ 5%

Applications Notes

Each investigator should determine their own optimal working dilution for specific applications.

Isotype Control

Armenian Hamster IgG Isotype Control for In Vivo - Low Endotoxin [PIP] (ICH2251)

Antibodies Against Same Target

Anti-IFN gamma In Vivo Antibody - Low Endotoxin [XMG1.2] (ICH1141) Anti-IFN gamma In Vivo Antibody - Low Endotoxin [R4-6A2] (ICH1129)

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