Anti-Mouse CD120a (55R-170) In Vivo Antibody - Low Endotoxin

Product Specifications

Background

Tumor necrosis factor receptor superfamily, member 1A, (TNFRI) also known as TNFRSF1A or CD120A is the principal receptor through which many of the pro-inflammatory activities of TNF-alpha are mediated. TNFRI contains a death domain through which it interacts with other death-domain proteins to promote cellular responses. It regulates immune and inflammatory responses.

Product Name Alternative

Tumor necrosis factor receptor superfamily member 1A, Tnfrsf1a, TNF-R1, TNF-RI, p55, p60

UniProt

P25118

Host

Armenian Hamster

Reactivity

Mouse

Immunogen

Recombinant Mouse TNF RI Extracellular Domain

Target

CD120a

Isotype

IgG1

Clone

55R-170

Applications

Immunoprecipitation, Western Blot, Blocking, Functional Assays, Flow Cytometry, Neutralization

Purification Method

This monoclonal antibody was purified using Protein A

Concentration

1.0 mg/mL

Endotoxin

≤ 1.0 EU/mg as determined by the LAL method

Purity

>95% by SDS-PAGE and HPLC

Buffer

ICH3001-100ml ICH3002-100ml ICH3003-100ml

References & Citations

Uncoupling immune trajectories of response and adverse events from anti-PD-1 immunotherapy in hepatocellular carcinoma

Shipping Conditions

Blue ice

Storage Conditions

Anti-CD120a In Vivo Antibody - Low Endotoxin (55R-170) is stable for at least one week when stored sterile at 2-8°C. For long term storage aseptically aliquot in working volumes without diluting and store at –20°C in a manual defrost freezer. Avoid Repeated Freeze Thaw Cycles.