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Bulk Anti-Human CD62L (DREG56) Antibody

Product Specifications

Background

L-selectin, also known as CD62L, is a cell adhesion molecule consisting of a large, highly glycosylated, extracellular domain found on leukocytes. It belongs to the selectin family of proteins, which recognise sialylated carbohydrate groups. L-selectin acts as a "homing receptor" for leukocytes to enter secondary lymphoid tissues via the high endothelial venules. L-selectin is an effective marker for separating lymphoid progenitors from myeloid progenitors and hematopoietic stem cells in bone marrow.

Product Name Alternative

L-selectin, SELL, Leukocyte adhesion molecule 1, LAM-11 Leukocyte surface antigen Leu-8, Leukocyte-endothelial cell adhesion molecule 1, LECAM1, Lymph node homing receptor1, TQ12, gp90-MEL, LNHR, LYAM1

UniProt

P14151

Host

Mouse

Reactivity

Human

Target

CD62L

Isotype

IgG1

Clone

DREG56

Applications

Western Blot, Blocking, Functional Assays, Flow Cytometry

Purification Method

This monoclonal antibody was purified using Protein A

Concentration

1.0 mg/mL

Endotoxin

≤ 1.0 EU/mg as determined by the LAL method

Purity

>95% by SDS-PAGE and HPLC

Buffer

ICH3001-100ml ICH3002-100ml ICH3003-100ml

Shipping Conditions

Blue ice

Storage Conditions

Anti-CD62L In Vivo Antibody - Low Endotoxin (DREG56) is stable for at least one week when stored sterile at 2-8°C. For long term storage aseptically aliquot in working volumes without diluting and store at –80°C. Avoid Repeated Freeze Thaw Cycles.

Specificity

Anti-CD62L In Vivo Antibody - Low Endotoxin (DREG56) recognizes an epitope on Human CD62L

Formulation

0.01 M phosphate buffered saline (PBS) pH 7.2, 150 mM NaCl with no carrier protein, potassium or preservatives added.

Antigen Distribution

Majority of B cells, naïve T cells, subset of memory T and NK cells, monocytes, granulocytes, thymocytes

Aggregation

Aggregation level ≤ 5%

Applications Notes

Each investigator should determine their own optimal working dilution for specific applications.

Isotype Control

Mouse IgG1 Isotype Control for In Vivo - Low Endotoxin [HKSP] (ICH2247)

Antibodies Against Same Target

Anti-CD62L In Vivo Antibody - Low Endotoxin [MEL-14] (ICH1060)

Curated Selection

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