Anti-Phospho-Tuberin/TSC2 (S981) Antibody
Boster Bio Anti-Phospho-Tuberin/TSC2 (S981) Antibody catalog # P00229. Tested in WB, IHC, ICC, IF applications. This antibody reacts with Human, Mouse, Rat.
Product Specifications
Background
Tuberous sclerosis 2 protein, also known as TSC2 or Tuberin is a protein that is in humans. The chromosomal location of this gene is 16p13.3. Mutations in this gene lead to tuberous sclerosis complex. Its gene product is believed to be a tumor suppressor and is able to stimulate specific GTPases. The protein associates with hamartin in a cytosolic complex, possibly acting as a chaperone for hamartin. This gene involved in microtubule-mediated protein transport, but this seems to be due to unregulated mTOR signaling. It stimulates weakly the intrinsic GTPase activity of the Ras-related proteins RAP1A and RAB5 in vitro.
Synonyms
LAM; TSC2; TSC4; Tuberin; tuberous sclerosis 2; Tuberous sclerosis 2 protein
Gene Name
TSC2
UniProt
P49815
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
A synthesized peptide derived from human Tuberin/TSC2 around the phosphorylation site of Ser981.
Clonality
Polyclonal
Applications
WB, IHC, ICC, IF
Purification
Protein A affinity purified.
Concentration
500 μg/mL
Form
Liquid
Storage Conditions
12 months from date of receipt, -20°C as supplied. 6 months 2 to 8°C after reconstitution. Avoid repeated freezing and thawing.
Contents
500 μg/mL antibody with PBS,0.02% NaN3, 1 mg BSA and 50% glycerol.
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