Anti-Phospho-RAD51 (T309) Antibody
Boster Bio Anti-Phospho-RAD51 (T309) Antibody catalog # P00088. Tested in WB, ICC, IF applications. This antibody reacts with Human, Mouse.
Product Specifications
Background
DNA repair protein RAD51 homolog 1, also known as RAD51A, is a human gene. The Rad51 gene, HsRAD51, is a homolog of RecA of Escherichia coli and functions in recombination and DNA repair. BRCA1 and BRCA2 proteins form a complex with Rad51, and these genes are thought to participate in a common DNA damage response pathway associated with the activation of homologous recombination and double-strand break repair. RAD51 is also found to interact with BRCA1 and BRCA2, which may be important for the cellular response to DNA damage. BRCA2 is shown to regulate both the intracellular localization and DNA-binding ability of this protein. Loss of these controls following BRCA2 inactivation may be a key event leading to genomic instability and tumorigenesis.
Synonyms
BRCC5; HRAD51; HsRad51; HsT16930; RAD51; RAD51 homolog A; RAD51A; RECA
Gene Name
RAD51
UniProt
Q06609
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
A synthesized peptide derived from human RAD51 around the phosphorylation site of Thr309.
Clonality
Polyclonal
Applications
WB, ICC, IF
Purification
Protein A affinity purified.
Concentration
500 μg/mL
Form
Liquid
Storage Conditions
12 months from date of receipt, -20°C as supplied. 6 months 2 to 8°C after reconstitution. Avoid repeated freezing and thawing.
Contents
500 μg/mL antibody with PBS,0.02% NaN3, 1 mg BSA and 50% glycerol.
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