Anti-Phospho-Connexin 43/GJA1 (S373) Antibody
Boster Bio Anti-Phospho-Connexin 43/GJA1 (S373) Antibody catalog # P00599-4. Tested in WB, IHC applications. This antibody reacts with Human, Mouse, Rat.
Product Specifications
Background
Connexin 43 (Cx43), also called GAP Junction Protein, alpha-1 (GJA1) . Connexin 43 is a member of the connexin gene family which abundantly expressed in the heart and liver and was mapped to 6q21-q23.2. Connexin43, the major protein of gap junctions in the heart, is targeted by several protein kinases that regulate myocardial cell-cell coupling. Mutations in the connexin43 gap-junction gene, which lead to abnormally regulated cell-cell communication, are associated with visceroatrial heterotaxia. Cx43 must also play a critical role in the physiology of hearing, presumably by participating in the recycling of potassium to the cochlear endolymph.
Synonyms
Connexin 43; CX43; DFNB38; Gap junction alpha 1 protein; GJA1; GJAL; ODDD
Gene Name
GJA1
UniProt
P17302
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
A synthesized peptide derived from human Connexin 43 / GJA1 around the phosphorylation site of Ser373.
Clonality
Polyclonal
Applications
WB, IHC
Purification
Protein A affinity purified.
Concentration
500 μg/mL
Form
Liquid
Storage Conditions
12 months from date of receipt, -20°C as supplied. 6 months 2 to 8°C after reconstitution. Avoid repeated freezing and thawing.
Contents
500 μg/mL antibody with PBS,0.02% NaN3, 1 mg BSA and 50% glycerol.
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