Anti-Phospho-Claudin 4/CLDN4 (Y208) Antibody
Boster Bio Anti-Phospho-Claudin 4/CLDN4 (Y208) Antibody catalog # P03683. Tested in WB, IHC applications. This antibody reacts with Human, Mouse, Rat.
Product Specifications
Background
The claudin superfamily consists of many structurally related proteins in humans. These proteins are important structural and functional components of tight junctions in paracellular transport. Claudins are located in both epithelial and endothelial cells in all tight junction-bearing tissues. Three classes of proteins are known to localize to tight junctions, including the claudins, Occludin and junction adhesion molecule. Claudins, which consist of four transmembrane domains and two extracellular loops make up tight junction strands. Claudin expression is highly restricted to specfic regions of different tissues and may have an important role in transcellular transport through tight junctions. Claudin-4 is not expressed in rat liver, whereas in pancreas, claudin-4 is localized to junctions of the duct epithelia and junctions of acinar cells. In the rat gut, claudin-4 displays highly restricted expression to colonic surface cells. The human claudin-4 gene maps to chromosome 7q11.23.
Synonyms
Claudin 4; Claudin 4-specific; CLDN4; CPE R; CPE receptor; CPER; CPETR; CPETR1; hCPE R; WBSCR8
Gene Name
CLDN4
UniProt
O14493
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
A synthesized peptide derived from human Claudin 4 around the phosphorylation site of Tyr208.
Clonality
Polyclonal
Applications
WB, IHC
Purification
Protein A affinity purified.
Concentration
500 μg/mL
Form
Liquid
Storage Conditions
12 months from date of receipt, -20°C as supplied. 6 months 2 to 8°C after reconstitution. Avoid repeated freezing and thawing.
Contents
500 μg/mL antibody with PBS,0.02% NaN3, 1 mg BSA and 50% glycerol.
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