Anti-Phospho-PKC Beta/PRKCB (S661) Antibody
Boster Bio Anti-Phospho-PKC Beta/PRKCB (S661) Antibody catalog # P01940. Tested in WB, IHC applications. This antibody reacts with Human, Mouse.
Product Specifications
Background
Protein kinase C beta type is an enzyme that in humans is encoded by the PRKCB gene. It is a member of the protein kinase C (PKC) gene family. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways. PKC family members also serve as major receptors for phorbol esters, a class of tumor promoters. This protein kinase has been reported to be involved in many different cellular functions, such as B cell activation, apoptosis induction, endothelial cell proliferation, and intestinal sugar absorption. It has been found that PRKCB activated by oxidative conditions in the cell, induces phosphorylation of p66 (SHC) and triggers mitochondrial accumulation of the protein after it is recognized by the prolyl isomerase PIN1.
Synonyms
PKC B; PKC beta; PKCB; PRKCB; PRKCB1; PRKCB2; Protein kinase C beta type; protein kinase C; beta
Gene Name
PRKCB
UniProt
P05771
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
A synthesized peptide derived from human PKC beta 1 around the phosphorylation site of Ser661.
Clonality
Polyclonal
Applications
WB, IHC
Purification
Protein A affinity purified.
Concentration
500 μg/mL
Form
Liquid
Storage Conditions
12 months from date of receipt, -20°C as supplied. 6 months 2 to 8°C after reconstitution. Avoid repeated freezing and thawing.
Contents
500 μg/mL antibody with PBS,0.02% NaN3, 1 mg BSA and 50% glycerol.
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