Anti-Phospho-FOXM1 (T600) Antibody
Boster Bio Anti-Phospho-FOXM1 (T600) Antibody catalog # P00659-1. Tested in WB, IHC, ICC, IF applications. This antibody reacts with Human, Mouse, Rat.
Product Specifications
Background
Forkhead box protein M1, also called FOXM1, is a protein that in humans is encoded by the FOXM1 gene. It is mapped to 12p13.33. The protein encoded by this gene is a member of the FOX family of transcription factors. FOXM1 is known to play a key role in cell cycle progression where endogenous FOXM1 expression peaks at S and G2/M phases and also in the control of cell proliferation. FOXM1 gene is now known as a human proto-oncogene. Abnormal upregulation of FOXM1 is involved in the oncogenesis of basal cell carcinoma, the most common human cancer worldwide. It was hypothesized that FOXM1 induces cancer initiation through stem/progenitor cell expansion. What's more, FOXM1 has been shown to modulate the epigenome. It was found that overexpression of FOXM1 "brain washes" normal cells to adopt cancer-like epigenome.
Synonyms
FKHL16; forkhead box M1; FOXM1; FOXM1B; HFH 11; HFH11; HNF 3; HNF 3/fork head homolog 11; INS 1; M phase phosphoprotein 2; MPHOSPH2; MPP 2; MPP2; PIG29; TGT3; Transcription factor Trident; TRIDENT; WIN
Gene Name
FOXM1
UniProt
Q08050
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
A synthesized peptide derived from human FOXM1 around the phosphorylation site of Thr600.
Clonality
Polyclonal
Applications
WB, IHC, ICC, IF
Purification
Protein A affinity purified.
Concentration
500 μg/mL
Form
Liquid
Storage Conditions
12 months from date of receipt, -20°C as supplied. 6 months 2 to 8°C after reconstitution. Avoid repeated freezing and thawing.
Contents
500 μg/mL antibody with PBS,0.02% NaN3, 1 mg BSA and 50% glycerol.
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