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Anti-Phospho-STAT3 (Y539) Antibody

Boster Bio Anti-Phospho-STAT3 (Y539) Antibody catalog # P00007-5. Tested in WB, IHC, ICC, IF applications. This antibody reacts with Human, Mouse, Rat.

Product Specifications

Background

The transcription factor, signal transducer and activator of transcription-3 (STAT-3) is the most pleiotropic member of the signal transducer and activator of transcription (STAT) family of transcription factors and mediates pivotal responses for the cytokine family. The mouse STAT3 gene contains 24 exons and spans 30 kb. The translation initiation codon is in exon 2, and the stop codon is in exon 24. STAT3 is mapped to 17q21. It contributes to various physiological processes. Hepatic STAT-3 signaling is thus essential for normal glucose homeostasis and may provide new therapeutic targets for diabetes mellitus.

Synonyms

Acute phase response factor; APRF; HIES; STAT3

Gene Name

STAT3

UniProt

P40763

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

A synthesized peptide derived from human STAT3 around the phosphorylation site of Tyr539.

Clonality

Polyclonal

Applications

WB, IHC, ICC, IF

Purification

Protein A affinity purified.

Concentration

500 μg/mL

Form

Liquid

Storage Conditions

12 months from date of receipt, -20°C as supplied. 6 months 2 to 8°C after reconstitution. Avoid repeated freezing and thawing.

Contents

500 μg/mL antibody with PBS,0.02% NaN3, 1 mg BSA and 50% glycerol.

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