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Anti-Phospho-EZH2 (T416) Antibody

Boster Bio Anti-Phospho-EZH2 (T416) Antibody catalog # P00050-1. Tested in IHC, ICC, IF applications. This antibody reacts with Human, Mouse, Rat.

Product Specifications

Background

Enhancer of zeste homolog 2 (EZH2) is a histone-lysine N-methyltransferase enzyme encoded by EZH2 gene. It is mapped to 7q36.1. This gene encodes a member of the Polycomb-group (PcG) family. PcG family members form multimeric protein complexes, which are involved in maintaining the transcriptional repressive state of genes over successive cell generations. This protein associates with the embryonic ectoderm development protein, the VAV1 oncoprotein, and the X-linked nuclear protein. This protein may play a role in the hematopoietic and central nervous systems. Multiple alternatively splcied transcript variants encoding distinct isoforms have been identified for this gene.

Synonyms

Enhancer of zeste homolog 2; ENX 1; ENX-1; EZH1; EZH2; KMT6; Lysine N methyltransferase 6

Gene Name

EZH2

UniProt

Q15910

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

A synthesized peptide derived from human EZH2 around the phosphorylation site of Thr416.

Clonality

Polyclonal

Applications

IHC, ICC, IF

Purification

Protein A affinity purified.

Concentration

500 μg/mL

Form

Liquid

Storage Conditions

12 months from date of receipt, -20°C as supplied. 6 months 2 to 8°C after reconstitution. Avoid repeated freezing and thawing.

Contents

500 μg/mL antibody with PBS,0.02% NaN3, 1 mg BSA and 50% glycerol.

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