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Anti-Phospho-SPHK2 (S387) Antibody

Boster Bio Anti-Phospho-SPHK2 (S387) Antibody catalog # P01382. Tested in WB, IHC applications. This antibody reacts with Human, Mouse, Rat.

Product Specifications

Background

Sphingosine kinase 2 is a protein that in humans is encoded by the SPHK2 gene. This gene encodes one of two sphingosine kinase isozymes that catalyze the phosphorylation of sphingosine into sphingosine 1-phosphate. Sphingosine 1-phosphate mediates many cellular processes including migration, proliferation and apoptosis, and also plays a role in several types of cancer by promoting angiogenesis and tumorigenesis. The encoded protein may play a role in breast cancer proliferation and chemoresistance. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

Synonyms

SK 2; sphingosine kinase 2; SPHK2; SPK 2

Gene Name

SPHK2

UniProt

Q9NRA0

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

A synthesized peptide derived from human SPHK2 around the phosphorylation site of Ser387.

Clonality

Polyclonal

Applications

WB, IHC

Purification

Protein A affinity purified.

Concentration

500 μg/mL

Form

Liquid

Storage Conditions

12 months from date of receipt, -20°C as supplied. 6 months 2 to 8°C after reconstitution. Avoid repeated freezing and thawing.

Contents

500 μg/mL antibody with PBS,0.02% NaN3, 1 mg BSA and 50% glycerol.

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