Anti-Phospho-SMAD1 (S187) Antibody
Boster Bio Anti-Phospho-SMAD1 (S187) Antibody catalog # P00728-1. Tested in WB, IHC, ICC, IF applications. This antibody reacts with Human, Mouse.
Product Specifications
Background
SMADs are proteins that modulate the activity of transforming growth factor beta ligands. The SMADs, often in complex with other SMADs/CoSMAD, act as transcription factors that regulate the expression of certain genes. It was concluded that targeted ubiquitination of SMADs may serve to control both embryonic development and a wide variety of cellular responses to TGF-beta signals. R-Smads or receptor regulated Smads are a class of proteins that include SMAD1, SMAD2, SMAD3, SMAD5, and SMAD8. In response to signals by the TGF-β superfamily of ligands these proteins associate with receptor kinases and are phosphorylated at an SSXS motif at their extreme C-terminus. These proteins then typically bind to the common mediator Smad or co-SMAD SMAD4.
Synonyms
BSP 1; BSP1; hSMAD1; JV4 1; JV41; MAD homolog 1; Mad related protein 1; MADH1; MADR1; Mothers against DPP homolog 1; SMAD 1; SMAD family member 1; SMAD1
Gene Name
SMAD1
UniProt
Q15797
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
A synthesized peptide derived from human Smad1 around the phosphorylation site of Ser187.
Clonality
Polyclonal
Applications
WB, IHC, ICC, IF
Purification
Protein A affinity purified.
Concentration
500 μg/mL
Form
Liquid
Storage Conditions
12 months from date of receipt, -20°C as supplied. 6 months 2 to 8°C after reconstitution. Avoid repeated freezing and thawing.
Contents
500 μg/mL antibody with PBS,0.02% NaN3, 1 mg BSA and 50% glycerol.
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