Anti-Phospho-PKC Delta/PRKCD (S645) Antibody
Boster Bio Anti-Phospho-PKC Delta/PRKCD (S645) Antibody catalog # P00822. Tested in WB, IHC, ICC, IF applications. This antibody reacts with Human, Mouse.
Product Specifications
Background
Protein kinase C delta type, also called PKCD, is an enzyme that in humans is encoded by the PRKCD gene. The PRKCD gene encodes a member of the protein kinase C family, members of which are critical for regulation of cell survival, proliferation, and apoptosis. This gene is mapped to 3p21.1. Studies both in human and mice demonstrate that this kinase is involved inB cell signaling and in the regulation of growth, apoptosis, and differentiation of a variety of cell types. PRKCD is also regulated by phosphorylation on various tyrosine residues including Y311 (by SRC) . It has been showed that PRKCD phosphorylates NLRC4 and that this phosphorylation is critical for inflammasome assembly. What’s more, it is also a part of a noncanonical WNT signaling cascade.
Synonyms
MAY1; PKC delta; PKCD; PRKCD; Protein kinase C delta type; protein kinase C; delta
Gene Name
PRKCD
UniProt
Q05655
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
A synthesized peptide derived from human PKC delta around the phosphorylation site of Ser645.
Clonality
Polyclonal
Applications
WB, IHC, ICC, IF
Purification
Protein A affinity purified.
Concentration
500 μg/mL
Form
Liquid
Storage Conditions
12 months from date of receipt, -20°C as supplied. 6 months 2 to 8°C after reconstitution. Avoid repeated freezing and thawing.
Contents
500 μg/mL antibody with PBS,0.02% NaN3, 1 mg BSA and 50% glycerol.
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