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Anti-Phospho-p70 S6K/RPS6KB1 (S371) Antibody

Boster Bio Anti-Phospho-p70 S6K/RPS6KB1 (S371) Antibody catalog # P01475-3. Tested in WB, IHC, ICC, IF applications. This antibody reacts with Human, Mouse, Rat.

Product Specifications

Background

Ribosomal protein S6 kinase beta-1 (S6K1), also known as p70S6 kinase (p70S6K, p70-S6K), is an enzyme (specifically, a protein kinase) that in humans is encoded by the RPS6KB1 gene. This gene encodes a member of the ribosomal S6 kinase family of serine/threonine kinases. The encoded protein responds to mTOR (mammalian target of rapamycin) signaling to promote protein synthesis, cell growth, and cell proliferation. Activity of this gene has been associated with human cancer. Alternatively spliced transcript variants have been observed. The use of alternative translation start sites results in isoforms with longer or shorter N-termini which may differ in their subcellular localizations. There are two pseudogenes for this gene on chromosome 17.

Synonyms

P70 alpha; p70 ribosomal S6 kinase alpha; p70 S6 kinase alpha; p70 S6K 1; p70 S6K alpha; p70 S6KA; p70 (S6K) ; p70 (S6K) alpha; p70S6K; P70S6K1; PS6K; Ribosomal protein S6 kinase I; RPS6KB1; S6K; S6K beta 1; S6K1; STK14A

Gene Name

RPS6KB1

UniProt

P23443

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

A synthesized peptide derived from human p70 S6 Kinase around the phosphorylation site of Ser371.

Clonality

Polyclonal

Applications

WB, IHC, ICC, IF

Purification

Protein A affinity purified.

Concentration

500 μg/mL

Form

Liquid

Storage Conditions

12 months from date of receipt, -20°C as supplied. 6 months 2 to 8°C after reconstitution. Avoid repeated freezing and thawing.

Contents

500 μg/mL antibody with PBS,0.02% NaN3, 1 mg BSA and 50% glycerol.

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