Anti-Phospho-TRPV4 (S824) Antibody
Boster Bio Anti-Phospho-TRPV4 (S824) Antibody catalog # P00565. Tested in ELISA applications. This antibody reacts with Human, Mouse, Rat.
Product Specifications
Background
TRPV4 (Transient Receptor Potential Cation Channel Subfamily V Member 4), also known as TRP12, OTRPC4 or VROAC, is a protein that in humans is encoded by the TRPV4 gene. This gene encodes TRPV4, a member of the OSM9-like transient receptor potential channel (OTRPC) subfamily in the transient receptor potential (TRP) superfamily of ion channels. By genomic sequence analysis, Liedtke et al. (2000) mapped the TRPV4 gene to chromosome 12q24.1. They mapped the mouse Trpv4 gene to distal chromosome 5 by radiation hybrid analysis. Wissenbach et al. (2000) found that hypoosmotic conditions rapidly activated TRP12, while hyperosmotic conditions inhibited the activity.Strotmann et al. (2000) showed that OTRPC4 was responsive to changes in extracellular osmolarity in the physiologically relevant range and was expressed in tissues exposed to changing osmotic environments.
Synonyms
Osm 9 like TRP channel 4; OTRPC4; TRP12; TRPV4; VR OAC; VRL 2; VRL2; VROAC
Gene Name
TRPV4
UniProt
Q9HBA0
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
A synthesized peptide derived from human TRPV4 (Accession Q9HBA0), corresponding to amino acid residues around Ser824.
Clonality
Polyclonal
Applications
ELISA
Purification
Protein A affinity purified.
Concentration
500 μg/mL
Form
Liquid
Storage Conditions
12 months from date of receipt, -20°C as supplied. 6 months 2 to 8°C after reconstitution. Avoid repeated freezing and thawing.
Applications Notes
ELISA, 1:100-1000
Contents
500 μg/mL antibody with PBS,0.02% NaN3, 1 mg BSA and 50% glycerol.
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