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Anti-Phospho-FGFR2 (S782) Antibody

Boster Bio Anti-Phospho-FGFR2 (S782) Antibody catalog # P00231-1. Tested in WB, IHC, ICC, IF applications. This antibody reacts with Human, Mouse, Rat.

Product Specifications

Background

Fibroblast growth factor receptor 2 (FGFR2) is a receptor for fibroblast growth factor encoded on a gene residing on chromosome 10. FGFR2 has also been designated as CD332. FGFR2 is a membrane-spanning tyrosine kinase that serves as a high affinity receptor for several members of the fibroblast growth factor (FGF) family. Its signals are absolutely required for vertebrate limb induction and that an FGFR2 signal is essential for the reciprocal regulation loop between FGF8 and FGF10 during limb induction. FGFR2 contributes to the outgrowth, differentiation, and maintenance of the inner cell mass and raise the possibility that this activity is mediated by FGF4 signals transmitted by FGFR2. The role of early FGF signaling in pregastrulation development as a possible adaptation to mammalian (amniote) embryogenesis is discussed.

Synonyms

BEK; BFR 1; CD332; CEK3; CFD1; ECT1; FGFR 2; FGFR2; JWS; K SAM; KGFR; KSAM; TK14; TK25

Gene Name

FGFR2

UniProt

P21802

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

A synthesized peptide derived from human FGFR2 around the phosphorylation site of Ser782.

Clonality

Polyclonal

Applications

WB, IHC, ICC, IF

Purification

Protein A affinity purified.

Concentration

500 μg/mL

Form

Liquid

Storage Conditions

12 months from date of receipt, -20°C as supplied. 6 months 2 to 8°C after reconstitution. Avoid repeated freezing and thawing.

Contents

500 μg/mL antibody with PBS,0.02% NaN3, 1 mg BSA and 50% glycerol.

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