Anti-Phospho-LAT (Y161) Antibody
Boster Bio Anti-Phospho-LAT (Y161) Antibody catalog # P01654-1. Tested in WB, IHC, ICC, IF applications. This antibody reacts with Human, Mouse, Rat.
Product Specifications
Background
Linker for activation of T cells, also known as LAT, is a protein which in humans is encoded by the LAT gene. This gene is mapped to 16p11.2. The protein encoded by this gene is phosphorylated by ZAP-70/Syk protein tyrosine kinases following activation of the T-cell antigen receptor (TCR) signal transduction pathway. This transmembrane protein localizes to lipid rafts and acts as a docking site for SH2 domain-containing proteins. Upon phosphorylation, this protein recruits multiple adaptor proteins and downstream signaling molecules into multimolecular signaling complexes located near the site of TCR engagement.
Synonyms
LAT; LAT1; p36 38; pp36
Gene Name
LAT
UniProt
O43561
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
A synthesized peptide derived from human LAT around the phosphorylation site of Tyr161.
Clonality
Polyclonal
Applications
WB, IHC, ICC, IF
Purification
Protein A affinity purified.
Concentration
500 μg/mL
Form
Liquid
Storage Conditions
12 months from date of receipt, -20°C as supplied. 6 months 2 to 8°C after reconstitution. Avoid repeated freezing and thawing.
Contents
500 μg/mL antibody with PBS,0.02% NaN3, 1 mg BSA and 50% glycerol.
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