Anti-Phospho-TTK (T676) Antibody
Boster Bio Anti-Phospho-TTK (T676) Antibody catalog # P01132. Tested in WB, IHC applications. This antibody reacts with Human, Mouse, Rat.
Product Specifications
Background
Dual specificity protein kinase TTK is a protein that in humans is encoded by the XRCC2 gene. This gene is mapped to 6q14.1. This gene encodes a dual specificity protein kinase with the ability to phosphorylate tyrosine, serine and threonine. Associated with cell proliferation, this protein is essential for chromosome alignment at the centromere during mitosis and is required for centrosome duplication. It has been found to be a critical mitotic checkpoint protein for accurate segregation of chromosomes during mitosis. Tumorigenesis may occur when this protein fails to degrade and produces excess centrosomes resulting in aberrant mitotic spindles. Alternative splicing results in multiple transcript variants.
Synonyms
ESK; MPS1; MPS1L1; PYT; TTK; TTK protein kinase
Gene Name
TTK
UniProt
P33981
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
A synthesized peptide derived from human TTK around the phosphorylation site of Thr676.
Clonality
Polyclonal
Applications
WB, IHC
Purification
Protein A affinity purified.
Concentration
500 μg/mL
Form
Liquid
Storage Conditions
12 months from date of receipt, -20°C as supplied. 6 months 2 to 8°C after reconstitution. Avoid repeated freezing and thawing.
Contents
500 μg/mL antibody with PBS,0.02% NaN3, 1 mg BSA and 50% glycerol.
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
MBS1383518-05 0.02 mg (Baculovirus)
Recombinant Mouse Zinc finger protein 436 (Znf436)
Ask
View Details