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Anti-Phospho-ATG14 (T429) Antibody

Boster Bio Anti-Phospho-ATG14 (T429) Antibody catalog # P03546. Tested in WB, IHC applications. This antibody reacts with Human, Mouse, Rat.

Product Specifications

Background

ATG14 (also known as beclin-1-associated autophagy-related key regulator (Barkor) or ATG14L), an essential autophagy-specific regulator of the class III phosphatidylinositol 3-kinase complex, promotes membrane tethering of protein-free liposomes, and enhances hemifusion and full fusion of proteoliposomes reconstituted with the target (t) -SNAREs (soluble N-ethylmaleimide-sensitive factor attachment protein receptors) syntaxin 17 (STX17) and SNAP29, and the vesicle (v) -SNARE VAMP8 (vesicle-associated membrane protein 8) . ATG14 binds to the SNARE core domain of STX17 through its coiled-coil domain, and stabilizes the STX17-SNAP29 binary t-SNARE complex on autophagosomes.

Synonyms

ATG14; Atg14L; Barkor; KIAA0831

Gene Name

ATG14

UniProt

Q6ZNE5

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

A synthesized peptide derived from human Atg14 around the phosphorylation site of Thr429.

Clonality

Polyclonal

Applications

WB, IHC

Purification

Protein A affinity purified.

Concentration

500 μg/mL

Form

Liquid

Storage Conditions

12 months from date of receipt, -20°C as supplied. 6 months 2 to 8°C after reconstitution. Avoid repeated freezing and thawing.

Contents

500 μg/mL antibody with PBS,0.02% NaN3, 1 mg BSA and 50% glycerol.

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