Anti-Phospho-ATP1A1 (Y260) Antibody

The protein encoded by this gene belongs to the family of P-type cation transport ATPases, and to the subfamily of Na+/K+ -ATPases. Na+/K+ -ATPase is an integral membrane protein responsible for establishing and maintaining the electrochemical gradients of Na and K ions across the plasma membrane. These gradients are essential for osmoregulation, for sodium-coupled transport of a variety of organic and inorganic molecules, and for electrical excitability of nerve and muscle. This enzyme is composed of two subunits, a large catalytic subunit (alpha) and a smaller glycoprotein subunit (beta) . The catalytic subunit of Na+/K+ -ATPase is encoded by multiple genes. This gene encodes an alpha 1 subunit. Multiple transcript variants encoding different isoforms have been found for this gene.

ATP1A1; Na (+) /K (+) ATPase 1; Na (+) /K (+) ATPase alpha 1 subunit; Na+/K+ ATPase 1; Sodium potassium ATPase alpha 1 polypeptide; Sodium pump subunit alpha 1