Anti-Phospho-RIP3/RIPK3 (S199) Antibody
Boster Bio Anti-Phospho-RIP3/RIPK3 (S199) Antibody catalog # P00202. Tested in IHC, ICC, IF applications. This antibody reacts with Human, Rat.
Product Specifications
Background
Receptor-interacting serine/threonine-protein kinase 3 (RIPK3), also known as RIP3 is an enzyme that in humans is encoded by the RIPK3 gene. This gene is mapped to 14q12. The product of this gene is a member of the receptor-interacting protein (RIP) family of serine/threonine protein kinases, and contains a C-terminal domain unique from other RIP family members. The encoded protein is predominantly localized to the cytoplasm, and can undergo nucleocytoplasmic shuttling dependent on novel nuclear localization and export signals. It is a component of the tumor necrosis factor (TNF) receptor-I signaling complex, and can induce apoptosis and weakly activate the NF-kappaB transcription factor.
Synonyms
Receptor interacting protein 3; RIP 3; RIP like protein kinase 3; RIP3; RIPK3
Gene Name
RIPK3
UniProt
Q9Y572
Host
Rabbit
Reactivity
Human, Rat
Immunogen
A synthesized peptide derived from human RIPK3 around the phosphorylation site of Ser199.
Clonality
Polyclonal
Applications
IHC, ICC, IF
Purification
Protein A affinity purified.
Concentration
500 μg/mL
Form
Liquid
Storage Conditions
12 months from date of receipt, -20°C as supplied. 6 months 2 to 8°C after reconstitution. Avoid repeated freezing and thawing.
Contents
500 μg/mL antibody with PBS,0.02% NaN3, 1 mg BSA and 50% glycerol.
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