Anti-Phospho-FGFR2 (Y769) Antibody
Boster Bio Anti-Phospho-FGFR2 (Y769) Antibody catalog # P00231. Tested in WB, IHC applications. This antibody reacts with Human, Mouse, Rat, Monkey.
Product Specifications
Background
Fibroblast growth factor receptor 2 (FGFR2) is a receptor for fibroblast growth factor encoded on a gene residing on chromosome 10. FGFR2 has also been designated as CD332. FGFR2 is a membrane-spanning tyrosine kinase that serves as a high affinity receptor for several members of the fibroblast growth factor (FGF) family. Its signals are absolutely required for vertebrate limb induction and that an FGFR2 signal is essential for the reciprocal regulation loop between FGF8 and FGF10 during limb induction. FGFR2 contributes to the outgrowth, differentiation, and maintenance of the inner cell mass and raise the possibility that this activity is mediated by FGF4 signals transmitted by FGFR2. The role of early FGF signaling in pregastrulation development as a possible adaptation to mammalian (amniote) embryogenesis is discussed.
Synonyms
BEK; BFR 1; CD332; CEK3; CFD1; ECT1; FGFR 2; FGFR2; JWS; K SAM; KGFR; KSAM; TK14; TK25
Gene Name
FGFR2
UniProt
P21802
Host
Rabbit
Reactivity
Human, Mouse, Rat, Monkey
Immunogen
A synthesized peptide derived from human FGFR2 around the phosphorylation site of Tyr769.
Clonality
Polyclonal
Applications
WB, IHC
Purification
Protein A affinity purified.
Concentration
500 μg/mL
Form
Liquid
Storage Conditions
12 months from date of receipt, -20°C as supplied. 6 months 2 to 8°C after reconstitution. Avoid repeated freezing and thawing.
Contents
500 μg/mL antibody with PBS,0.02% NaN3, 1 mg BSA and 50% glycerol.
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