Anti-Phospho-GRK2 (S670) Antibody
Boster Bio Anti-Phospho-GRK2 (S670) Antibody catalog # P32388. Tested in WB, ICC, IF applications. This antibody reacts with Human, Mouse, Rat.
Product Specifications
Background
Beta adrenergic receptor kinase (also referred to as βARK or BARK) is a serine/threonine intracellular kinase. The product of this gene phosphorylates the beta-2-adrenergic receptor and appears to mediate agonist-specific desensitization observed at high agonist concentrations. This protein is an ubiquitous cytosolic enzyme that specifically phosphorylates the activated form of the beta-adrenergic and related G-protein-coupled receptors. Abnormal coupling of beta-adrenergic receptor to G protein is involved in the pathogenesis of the failing heart.
Synonyms
ADRBK1; BARK; BARK1; Beta ARK 1; BETA ARK1; GRK2
Gene Name
GRK2
UniProt
P25098
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
A synthesized peptide derived from human GRK2 around the phosphorylation site of Ser670.
Clonality
Polyclonal
Applications
WB, ICC, IF
Purification
Protein A affinity purified.
Concentration
500 μg/mL
Form
Liquid
Storage Conditions
12 months from date of receipt, -20°C as supplied. 6 months 2 to 8°C after reconstitution. Avoid repeated freezing and thawing.
Contents
500 μg/mL antibody with PBS,0.02% NaN3, 1 mg BSA and 50% glycerol.
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