Anti-Phospho-RET (Y1062) Antibody
Boster Bio Anti-Phospho-RET (Y1062) Antibody catalog # P00293. Tested in WB, ICC, IF applications. This antibody reacts with Human, Mouse, Rat.
Product Specifications
Background
The RET proto-oncogene encodes a receptor tyrosine kinase for members of the glial cell line-derived neurotrophic factor (GDNF) family of extracellular signalling molecules. Binding of ligands such as GDNF (glial cell-line derived neurotrophic factor) and other related proteins to the encoded receptor stimulates receptor dimerization and activation of downstream signaling pathways that play a role in cell differentiation, growth, migration and survival. The encoded receptor is important in development of the nervous system, and the development of organs and tissues derived from the neural crest. This proto-oncogene can undergo oncogenic activation through both cytogenetic rearrangement and activating point mutations. Mutations in this gene are associated with Hirschsprung disease and central hypoventilation syndrome and have been identified in patients with renal agenesis.
Synonyms
Ret proto-oncogene; CDHF12; CDHR16; HSCR1; MEN2A; MEN2B; MTC1; PTC-ELE1; RET
Gene Name
RET
UniProt
P07949
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
A synthesized peptide derived from human Ret around the phosphorylation site of Tyr1062.
Clonality
Polyclonal
Applications
WB, ICC, IF
Purification
Protein A affinity purified.
Concentration
500 μg/mL
Form
Liquid
Storage Conditions
12 months from date of receipt, -20°C as supplied. 6 months 2 to 8°C after reconstitution. Avoid repeated freezing and thawing.
Contents
500 μg/mL antibody with PBS,0.02% NaN3, 1 mg BSA and 50% glycerol.
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