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Anti-Phospho-ATR (S428) Antibody

Boster Bio Anti-Phospho-ATR (S428) Antibody catalog # P00262. Tested in WB, IHC applications. This antibody reacts with Human, Mouse, Rat.

Product Specifications

Background

Serine/threonine-protein kinase ATR also known as ataxia telangiectasia and Rad3-related protein (ATR) or FRAP-related protein 1 (FRP1) is an enzyme that, in humans, is encoded by the ATR gene. The protein encoded by this gene is a serine/threonine kinase and DNA damage sensor, activating cell cycle checkpoint signaling upon DNA stress. The encoded protein can phosphorylate and activate several proteins involved in the inhibition of DNA replication and mitosis, and can promote DNA repair, recombination, and apoptosis. This protein is also important for fragile site stability and centrosome duplication. Defects in this gene are a cause of Seckel syndrome 1.

Synonyms

ATR; FRAP related protein 1; FRP1; MEC1; SCKL; SCKL1

Gene Name

ATR

UniProt

Q13535

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

A synthesized peptide derived from human ATR around the phosphorylation site of Ser428.

Clonality

Polyclonal

Applications

WB, IHC

Purification

Protein A affinity purified.

Concentration

500 μg/mL

Form

Liquid

Storage Conditions

12 months from date of receipt, -20°C as supplied. 6 months 2 to 8°C after reconstitution. Avoid repeated freezing and thawing.

Product Datasheet

https://www.bosterbio.com/datasheet?sku=P00262

Product MSDS

https://www.bosterbio.com/msds?sku=P00262

Contents

500 μg/mL antibody with PBS,0.02% NaN3, 1 mg BSA and 50% glycerol.

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