Anti-Phospho-LKB1/STK11 (S428) Antibody
Boster Bio Anti-Phospho-LKB1/STK11 (S428) Antibody catalog # P00217-1. Tested in WB, IHC, ICC, IF applications. This antibody reacts with Human, Mouse, Monkey.
Product Specifications
Background
Serine/threonine kinase 11 or LKB1 is a protein kinase which in humans is encoded by the STK11 gene. The STK11 gene, which encodes a member of the serine/threonine kinase, regulates cell polarity and functions as a tumour suppressor. STK11 is a primary upstream kinase of adenine monophosphate-activated protein kinase (AMPK), a necessary element in cell metabolism that is required for maintaining energy homeostasis. It has been found that LKB1 physically associates with p53 and regulates specific p53-dependent apoptosis pathways. The STK11 gene extends over 23 kb of genomic DNA and is composed of 9 exons, which are transcribed in telomere-to-centromere direction.
Synonyms
LKB1; PJS; serine/threonine kinase 11; STK11
Gene Name
STK11
UniProt
Q15831
Host
Rabbit
Reactivity
Human, Mouse, Monkey
Immunogen
A synthesized peptide derived from human LKB1 around the phosphorylation site of Ser428.
Clonality
Polyclonal
Applications
WB, IHC, ICC, IF
Purification
Protein A affinity purified.
Concentration
500 μg/mL
Form
Liquid
Storage Conditions
12 months from date of receipt, -20°C as supplied. 6 months 2 to 8°C after reconstitution. Avoid repeated freezing and thawing.
Contents
500 μg/mL antibody with PBS,0.02% NaN3, 1 mg BSA and 50% glycerol.
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