Anti-Phospho-mTOR (T2446) Antibody
Boster Bio Anti-Phospho-mTOR (T2446) Antibody catalog # P00003-3. Tested in WB applications. This antibody reacts with Human, Mouse, Rat.
Product Specifications
Background
The mammalian target of rapamycin (mTOR), also known as the mechanistic target of rapamycin and FK506-binding protein 12-rapamycin-associated protein 1 (FRAP1), is a kinase that in humans is encoded by theMTOR gene. The protein encoded by this gene belongs to a family of phosphatidylinositol kinase-related kinases. These kinases mediate cellular responses to stresses such as DNA damage and nutrient deprivation. This protein acts as the target for the cell-cycle arrest and immunosuppressive effects of the FKBP12-rapamycin complex. The ANGPTL7 gene is located in an intron of this gene.
Synonyms
FLJ44809; FRAP; FRAP1; FRAP2; Mammalian target of rapamycin; MTOR; RAFT1; Rapamycin target protein 1; RAPT1
Gene Name
MTOR
UniProt
P42345
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
A synthesized peptide derived from human mTOR around the phosphorylation site of Thr2446.
Clonality
Polyclonal
Applications
WB
Purification
Protein A affinity purified.
Concentration
500 μg/mL
Form
Liquid
Storage Conditions
12 months from date of receipt, -20°C as supplied. 6 months 2 to 8°C after reconstitution. Avoid repeated freezing and thawing.
Applications Notes
Western blot, 1:500-2000
Contents
500 μg/mL antibody with PBS,0.02% NaN3, 1 mg BSA and 50% glycerol.
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