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Anti-Phospho-JAK3 (Y981) Antibody

Boster Bio Anti-Phospho-JAK3 (Y981) Antibody catalog # P02598. Tested in WB, IHC, ICC, IF applications. This antibody reacts with Human, Mouse, Rat, Monkey.

Product Specifications

Background

Tyrosine-protein kinase JAK3 is an enzyme that in humans is encoded by the JAK3 gene. It is mapped to 19p13.11. The protein encoded by this gene is a member of the Janus kinase (JAK) family of tyrosine kinases involved in cytokine receptor-mediated intracellular signal transduction. It is predominantly expressed in immune cells and transduces a signal in response to its activation via tyrosine phosphorylation by interleukin receptors. Mutations in this gene are associated with autosomal SCID (severe combined immunodeficiency disease) .

Synonyms

Janus kinase 3; JAK-3_HUMAN; JAKL; L-JAK; LJAK; JAK3

Gene Name

JAK3

UniProt

P52333

Host

Rabbit

Reactivity

Human, Mouse, Rat, Monkey

Immunogen

A synthesized peptide derived from human JAK3 around the phosphorylation site of Tyr981.

Clonality

Polyclonal

Applications

WB, IHC, ICC, IF

Purification

Protein A affinity purified.

Concentration

500 μg/mL

Form

Liquid

Storage Conditions

12 months from date of receipt, -20°C as supplied. 6 months 2 to 8°C after reconstitution. Avoid repeated freezing and thawing.

Contents

500 μg/mL antibody with PBS,0.02% NaN3, 1 mg BSA and 50% glycerol.

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