Anti-Phospho-HER2/ERBB2 (Y1248) Antibody
Boster Bio Anti-Phospho-HER2/ERBB2 (Y1248) Antibody catalog # P00010-2. Tested in WB, IHC, ICC, IF applications. This antibody reacts with Human, Mouse, Rat.
Product Specifications
Background
Receptor tyrosine-protein kinase erbB-2, also known as CD340 (cluster of differentiation 340), proto-oncogene Neu, Erbb2 (rodent), or ERBB2 (human), is a protein that in humans is encoded by the ERBB2 gene. And it is also frequently called HER2 (from human epidermal growth factor receptor 2) or HER2/neu. This gene encodes a member of the epidermal growth factor (EGF) receptor family of receptor tyrosine kinases. This protein has no ligand binding domain of its own and therefore cannot bind growth factors. Amplification and/or overexpression of this gene has been reported in numerous cancers, including breast and ovarian tumors. Alternative splicing results in several additional transcript variants, some encoding different isoforms and others that have not been fully characterized.
Synonyms
CD340; ERBB2; HER 2; HER 2/neu; HER2; MLN 19; MLN19; NEU; NGL; p185; p185erbB2; Proto oncogene c ErbB 2; Proto oncogene Neu; TKR1
Gene Name
ERBB2
UniProt
P04626
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
A synthesized peptide derived from human HER2/ErbB2 around the phosphorylation site of Tyr1248.
Clonality
Polyclonal
Applications
WB, IHC, ICC, IF
Purification
Protein A affinity purified.
Concentration
500 μg/mL
Form
Liquid
Storage Conditions
12 months from date of receipt, -20°C as supplied. 6 months 2 to 8°C after reconstitution. Avoid repeated freezing and thawing.
Contents
500 μg/mL antibody with PBS,0.02% NaN3, 1 mg BSA and 50% glycerol.
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