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Anti-Phospho-IRAK1 (T387) Antibody

Boster Bio Anti-Phospho-IRAK1 (T387) Antibody catalog # P01021. Tested in WB, IHC applications. This antibody reacts with Human, Mouse, Rat.

Product Specifications

Background

Interleukin-1 receptor-associated kinase 1, also called IRAK1, is an enzyme that in humans is encoded by the IRAK1 gene. By radiation hybrid analysis, this gene is mapped to chromosome Xq28. Serine/threonine-protein kinase plays a critical role in initiating innate immune response against foreign pathogens. This gene involved in Toll-like receptor (TLR) and IL-1R signaling pathways. This gene encodes the interleukin-1 receptor-associated kinase 1, one of two putative serine/threonine kinases that become associated with the interleukin-1 receptor (IL1R) upon stimulation. This gene is partially responsible for IL1-induced upregulation of the transcription factor NF-kappa B.

Synonyms

IRAK; IRAK 1; IRAK1; pelle

Gene Name

IRAK1

UniProt

P51617

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

A synthesized peptide derived from human IRAK1 around the phosphorylation site of Thr387.

Clonality

Polyclonal

Applications

WB, IHC

Purification

Protein A affinity purified.

Concentration

500 μg/mL

Form

Liquid

Storage Conditions

12 months from date of receipt, -20°C as supplied. 6 months 2 to 8°C after reconstitution. Avoid repeated freezing and thawing.

Contents

500 μg/mL antibody with PBS,0.02% NaN3, 1 mg BSA and 50% glycerol.

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