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Anti-Phospho-VEGFR3/FLT4 (Y1230) Antibody

Boster Bio Anti-Phospho-VEGFR3/FLT4 (Y1230) Antibody catalog # P01276. Tested in IHC, ICC, IF applications. This antibody reacts with Human, Mouse, Rat.

Product Specifications

Background

Fms-related tyrosine kinase 4, also known as FLT4 or VEGFR3, is a protein which in humans is encoded by the FLT4 gene. It is mapped to 5q35.3. This gene encodes a tyrosine kinase receptor for vascular endothelial growth factors C and D. The protein is thought to be involved in lymphangiogenesis and maintenance of the lymphatic endothelium. FLT4 has an essential role in the development of the embryonic cardiovascular system before the emergence of the lymphatic vessels. It has been found that FLT4, which provides proangiogenic signaling when expressed on endothelium, may also have antiangiogenic properties when expressed at an avascular site by nonendothelial cells. FLT4 is also regarded as a regulator of vascular network formation.

Synonyms

FLT 4; FLT4; FLT41; Fms like tyrosine kinase 4; fms related tyrosine kinase 4; LMPH1A; PCL; VEGFR 3; VEGFR3

Gene Name

FLT4

UniProt

P35916

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

A synthesized peptide derived from human VEGFR3 around the phosphorylation site of Tyr1230.

Clonality

Polyclonal

Applications

IHC, ICC, IF

Purification

Protein A affinity purified.

Concentration

500 μg/mL

Form

Liquid

Storage Conditions

12 months from date of receipt, -20°C as supplied. 6 months 2 to 8°C after reconstitution. Avoid repeated freezing and thawing.

Contents

500 μg/mL antibody with PBS,0.02% NaN3, 1 mg BSA and 50% glycerol.

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