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Anti-Phospho-SMAD3 (S423+S425) Antibody

Boster Bio Anti-Phospho-SMAD3 (S423+S425) Antibody catalog # P00059-2. Tested in WB, IHC, ICC, IF applications. This antibody reacts with Human, Mouse, Rat.

Product Specifications

Background

Mothers against decapentaplegic homolog 3 also known as SMAD family member 3 or SMAD3 is a protein that in humans is encoded by the SMAD3 gene. SMAD3 is a member of the SMAD family of proteins. It is located in 15q22.33. And it mediates the signals from the transforming growth factor beta (TGF-β) super family ligands that regulate cell proliferation, differentiation and death. Based on its essential role in TGF beta signaling pathway, SMAD3 has been related with tumor growth in cancer development.

Synonyms

HMAD 3; hSMAD3; HSPC193; HsT17436; JV15 2; MAD homolog 3; Mad3; MADH3; Mothers against DPP homolog 3; SMAD 3; SMAD family member 3; SMAD3

Gene Name

SMAD3

UniProt

P84022

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

A synthesized peptide derived from human Smad3 around the phosphorylation site of Ser423+Ser425.

Clonality

Polyclonal

Applications

WB, IHC, ICC, IF

Purification

Protein A affinity purified.

Concentration

500 μg/mL

Form

Liquid

Storage Conditions

12 months from date of receipt, -20°C as supplied. 6 months 2 to 8°C after reconstitution. Avoid repeated freezing and thawing.

Contents

500 μg/mL antibody with PBS,0.02% NaN3, 1 mg BSA and 50% glycerol.

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