Anti-Phospho-AKT1/2/3 (T308) Antibody
Boster Bio Anti-Phospho-AKT1/2/3 (T308) Antibody catalog # P00024-8. Tested in WB, IHC, ICC, IF applications. This antibody reacts with Human, Mouse, Rat.
Product Specifications
Background
Akt, also referred to as PKB or Rac, plays a critical role in controlling survival and apoptosis. This protein kinase is activated by insulin and various growth and survival factors to function in a wortmannin-sensitive pathway involving PI3 kinase. Akt is activated by phospholipid binding and activation loop phosphorylation at Thr308 by PDK1 and by phosphorylation within the carboxy terminus at Ser473. The previously elusive PDK2 responsible for phosphorylation of Akt at Ser473 has been identified as mammalian target of rapamycin (mTOR) in a rapamycin-insensitive complex with rictor and Sin1.
Synonyms
AKT; AKT1; PKB; PKB ALPHA; PRKBA; Protein kinase B; Proto oncogene c Akt; RAC; RAC ALPHA; RAC PK alpha; AKT2; PKB beta; PKBB; PKBBETA; PRKBB; Protein kinase Akt 2; Protein kinase B beta; RAC BETA; RAC PK beta; AKT3; PKB GAMMA; PKBG; PRKBG; Protein kinase Akt 3; Protein kinase B gamma; RAC gamma; RAC PK gamma; STK 2
Gene Name
AKT1/2/3
UniProt
P31749/P31751/Q9Y243
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
A synthesized peptide derived from human Akt around the phosphorylation site of Thr308.
Clonality
Polyclonal
Applications
WB, IHC, ICC, IF
Purification
Protein A affinity purified.
Concentration
500 μg/mL
Form
Liquid
Storage Conditions
12 months from date of receipt, -20°C as supplied. 6 months 2 to 8°C after reconstitution. Avoid repeated freezing and thawing.
Contents
500 μg/mL antibody with PBS,0.02% NaN3, 1 mg BSA and 50% glycerol.
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
GTR15095546 1 Vial
Lentiviral human AMPH shRNA (UAS) - Lentiviral human AMPH shRNA (UAS, iRFP) (25)
Ask
View Details 
