Anti-Phospho-NF-κB p65/RELA (S536) Antibody
Boster Bio Anti-Phospho-NF-κB p65/RELA (S536) Antibody catalog # P00284-1. Tested in WB, IHC, ICC, IF, IP applications. This antibody reacts with Human, Rat.
Product Specifications
Background
Transcription factor p65, also known as NFKB3 or NF-kB p65, is a protein that in humans is encoded by the RELA gene. It is mapped to 11q13.1. NFKB is an essential transcription factor complex involved in all types of cellular processes, including cellular metabolism, chemotaxis, etc, and it may play a role in inflammatory conditions of the peripheral nervous system. Phosphorylation and acetylation of NFKB3 are crucial post-translational modifications required for NFKB activation. It has also been shown to modulate immune responses, and activation of NFKB3 is positively associated with multiple types of cancer. In addition to that, NFKB3 antagonizes TNFR1-JNK proliferative signals in epidermis and plays a nonredundant role in restraining epidermal growth.
Synonyms
NF Kappa B; NF κB; NFKB 3; NFKB p65; NFKB3; NF-κB; NF-κB3; p65; RELA; Transcription factor p65
Gene Name
RELA
UniProt
Q04206
Host
Rabbit
Reactivity
Human, Rat
Immunogen
A synthesized peptide derived from human NF- kappaB p65 around the phosphorylation site of Ser536.
Clonality
Polyclonal
Applications
WB, IHC, ICC, IF, IP
Purification
Protein A affinity purified.
Concentration
500 μg/mL
Form
Liquid
Storage Conditions
12 months from date of receipt, -20°C as supplied. 6 months 2 to 8°C after reconstitution. Avoid repeated freezing and thawing.
Contents
500 μg/mL antibody with PBS,0.02% NaN3, 1 mg BSA and 50% glycerol.
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