Anti-Alpha-Actinin ACTN2 Antibody (Monoclonal, 35A47)

Alpha-actinin was initially isolated from rabbit skeletal muscle as a factor that induces the gelation of F-actin and promotes the superprecipitation of actomyosin. Alpha actinins are actin-binding proteins that carry out different purposes in different different cell types. In myofibrillar cells, alpha-actinin constitutes a major component of Z-discs in striated muscle and of the functionally analogous dense bodies and dense plaques in smooth muscle. Alpha-actinin (alpha A) shares structural homology with spectrin and dystrophin.

Store at -20 ̊C for one year from date of receipt. After reconstitution, at 4 ̊C for one month. It can also be aliquotted and stored frozen at -20 ̊C for six months. Avoid repeated freeze-thaw cycles.