Mouse recombinant IL-22 (Interleukin-22) protein, AF
Interleukin 22 (IL-22) is an α-helical cytokine, predicts a molecular mass of 16.9 kDa. It is produced by T-helper (Th) -17 cells, γδ T cells, NKT cells and newly described innate lymphoid cells (ILCs) . Effects involve stimulation of cell survival, proliferation and synthesis of antimicrobials including S110, Reg3β, Reg3γ and defensins.
Product Specifications
Synonyms
IL-TIF, Cytokine ZCYTO18, If2b1, ILTIFa
Gene Name
Il22
UniProt
Q9JJY9
Reactivity
Mouse
Tag
His Tag (C-term)
Source
Escherichia coli
Applications
Cell Culture
Purification
>98% as determined by SDS-PAGE.
Endotoxin
<0.1 EU per 1 μg of the protein by the LAL method.
Bioactivity
Measure by its ability to induce IL-10 secretion in COLO205 cells. The ED50 for this effect is <0.3 ng/mL.
Form
Reconstitution
Molecular Weight
The protein has a calculated MW of 17.58 kDa. The protein migrates about 17 kDa under reducing condition (SDS-PAGE analysis) .
Storage Conditions
AA Sequence
Frequently Asked Questions
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