Mouse recombinant CXCL11 (C-X-C motif chemokine 11) protein, AF
C-X-C motif chemokine 11 (CXCL11) also named Interferon-gamma-inducible protein 9 (IP-9), which is a chemokine of the intercrine alpha family. CXCL11 is a 8.8 kDa protein containing 79 amino acid residues. To CXCR3, CXCL11 has higher affinity than CXCL10 and CXCL9 which plays a role in immune activation. CXCL11 induces the activation of T cells which is also a chemotaxis for T cells. CXCL11 is produced in response for IFN Family.
Product Specifications
Synonyms
Interferon Inducible T-Cell α Chemokine, I-TAC, B-R1
Gene Name
CXCL11
UniProt
Q9JHH5
Reactivity
Mouse
Tag
His Tag (N-term)
Source
Escherichia coli
Applications
Cell Culture
Purification
>98% as determined by SDS-PAGE.
Endotoxin
<0.1 EU per 1 μg of the protein by the LAL method.
Bioactivity
Measure by its ability to chemoattract BaF3 cells transfected with human CXCR3. The ED50 for this effect is <10 ng/mL.
Form
Reconstitution
Molecular Weight
The protein has a calculated MW of 9.92 kDa. The protein migrates about 11 kDa under reducing condition (SDS-PAGE analysis) .
Storage Conditions
AA Sequence
FLMFKQGRCLCIGPGMKAVKMAEIEKASVIYPSNGCDKVEVIVTMKAHKRQRCLDPRSKQARLIMQAIEKKNFLRRQNM with polyhistidine tag at the N-terminus.
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