Swine recombinant IL-15 (Interleukin-15) protein, AF
Interleukin 15 (IL-15) is a 12.65 kDa cytokine with 114 amino acid residues and is primarily produced from mononuclear phagocytes like dendritic cells, monocytes, and macrophages. IL-15 plays a critical role in the innate immune system when IL-15 binds to the IL-15 receptor. In addition, IL-15 mediates biological functions, such as the proliferation of natural killer cells and T cells, preventing the immune cells from apoptosis by activating STAT3 /JAK and PI3K/ALT signaling pathways.
Product Specifications
Synonyms
IL-T, IL15
Gene Name
IL15
UniProt
Q95253
Reactivity
Swine
Tag
His Tag (N-term)
Source
Escherichia coli
Applications
Cell Culture
Purification
>95% as determined by SDS-PAGE.
Endotoxin
<0.01 EU per 1 μg of the protein by the LAL method.
Bioactivity
Measure by its ability to induce proliferation in TF-1 cells. The ED50 for this effect is <5.5 ng/mL.
Form
Reconstitution
Molecular Weight
The protein has a calculated MW of 14.06 kDa. The protein migrates as 11-17 kDa under reducing condition (SDS-PAGE analysis) .
Storage Conditions
AA Sequence
Frequently Asked Questions
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