Human recombinant IL-30 (Interleukin-30) protein, AF
Interleukin 30 (IL-30) is a 27 kDa cytokine with 216 amino acid residues. IL-30, also known as IL-27A, forms a complex named IL-27 with Ebi3 and is secreted from cells of myeloid origin, such as monocytes, macrophages, and dendritic cells. IL-30 /Ebi3 complex mediates T-cell immunity, promoting Th1 differentiation, inhibiting Th2 differentiation, and inhibiting Th17 differentiation. IL-30 also can be secreted independently of Ebi3 and modulate bacteria-induced oxidative burst and cytokine production.
Product Specifications
Synonyms
IL-27-p28 subunit, IL27A; IL-27A; IL27p28
Gene Name
IL27
UniProt
Q8NEV9
Reactivity
Human
Tag
His Tag (C-term)
Source
Escherichia coli
Applications
Cell Culture
Purification
>98% as determined by SDS-PAGE.
Endotoxin
<0.1 EU per 1 μg of the protein by the LAL method.
Bioactivity
Testing in process
Form
Reconstitution
Molecular Weight
The protein has a calculated MW of 25.47 kDa. The protein migrates as 28 kDa under reducing condition (SDS-PAGE analysis) .
Storage Conditions
AA Sequence
Frequently Asked Questions
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