Mouse recombinant IL-33 (Interleukin-33) protein, AF
Interleukin 33 (IL-33) is a 17.65 kDa cytokine with 159 amino acid residues. IL-33 is a member of the IL-1 family and secreted from various cell types, such as mast cells, macrophages, endothelial cells, and epithelial cells. IL-33 activates NF-κB and MAPK signaling pathways that stimulate the secretion of type 2 cytokines like IL-5 and IL-13 when IL-33 binds to the ST2 receptor primarily expressed in mast cells and Th2 cells. In addition to Th type 2 responses, IL-33 participates in maintaining barrier tissue defense.
Product Specifications
Synonyms
IL-1 F11, NF-HEV, 9230117N10Rik
Gene Name
IL33
UniProt
Q8BVZ5
Reactivity
Mouse
Tag
His Tag (C-term)
Source
Escherichia coli
Applications
Cell Culture
Purification
>98% as determined by SDS-PAGE.
Endotoxin
<0.1 EU per 1 μg of the protein by the LAL method.
Bioactivity
Form
Reconstitution
Molecular Weight
The protein has a calculated MW of 18.51 kDa. The protein migrates as 17-25 kDa under reducing condition (SDS-PAGE analysis) .
Storage Conditions
AA Sequence
Frequently Asked Questions
Explore Other Products
Browse additional items from our catalog
