Human recombinant IL-34 (Interleukin-34) protein, AF
Interleukin-34 (IL-34) is a 30 kDa cytokine with 223 amino acid residues. IL-34 is a ligand of CSF-1R and secreted from CSF-1R expressing cells like myeloid cells, epithelial cells, endothelial cells, fibroblasts, and neurons. IL-34 mediates cell survival, proliferation, cytokine/chemokine expression, and migration via activating several signaling pathways. Moreover, it also plays a critical role in developing and maintaining the mononuclear phagocytic system.
Product Specifications
Synonyms
C16orf77, IL34
Gene Name
IL34
UniProt
Q6ZMJ4
Reactivity
Human
Tag
His Tag (C-term)
Source
Escherichia coli
Applications
Cell Culture
Purification
>98% as determined by SDS-PAGE.
Endotoxin
<0.1 EU per 1 μg of the protein by the LAL method.
Bioactivity
Measure by its ability to induce human peripheral blood monocytes (PBMCs) proliferation. The ED50 for this effect is <30 pg/mL.
Form
Reconstitution
Molecular Weight
The protein has a calculated MW of 26.17 kDa. The protein migrates as 30 kDa under reducing condition (SDS-PAGE analysis) .
Storage Conditions
AA Sequence
Frequently Asked Questions
Explore Other Products
Browse additional items from our catalog
Recombinant Human TNFSF4/OX40L Protein (His Tag)
Recombinant Human TNFSF4/OX40L Protein (His Tag)
ATG5 (Autophagy Marker) (ATG5/2492), CF405S conjugate, 0.1mg/mL
