Human recombinant CDNF (Cerebral dopamine neurotrophic factor) protein, AF
Cerebral dopamine neurotrophic factor (CDNF) also known as ARMETL1, which is a member of ARMET family. CDNF is a 20.9 kDa neurotrophic factor containing 187 residues that widely expressed in various tissues, including embryonic and postnatal brain. Besides, CDNF shows the ability to protect the degeneration of dopaminergic neurons in Parkinson’s disease, induced by 6-hydroxydopamine (6-OHDA) . Moreover, as a neurotrophic factor, CDNF also can repair the dopaminergic function of dopaminergic neurons.
Product Specifications
Synonyms
ARMETL1
Gene Name
CDNF
UniProt
Q49AH0
Reactivity
Human
Tag
His Tag (C-term)
Source
Escherichia coli
Applications
Cell Culture
Purification
>98% as determined by SDS-PAGE.
Endotoxin
<0.1 EU per 1 μg of the protein by the LAL method.
Bioactivity
Testing in process
Form
Reconstitution
Molecular Weight
The protein has a calculated MW of 19.26 kDa. The protein migrates as 18 kDa under reducing condition (SDS-PAGE analysis) .
Storage Conditions
AA Sequence
Frequently Asked Questions
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