Mouse recombinant Activin B protein, AF
Activin B is the cytokine of the TGF beta family, which is a 12.9 kDa protein containing 116 amino acid residues. Activin B has the wide variety of biological function including stem cell differentiation, inflammation, bone remodeling and neural development. It also has a role in regulation of FSH secretion. Activin B induces the phosphorylation of Smad which binds the smad binding element.
Product Specifications
Synonyms
Activin Beta B; Activin beta-B chain; INHBB; inhibin beta B
Gene Name
Inhbb
UniProt
Q04999
Reactivity
Mouse
Tag
His Tag (C-term)
Source
Escherichia coli
Applications
Cell Culture
Purification
>95% as determined by SDS-PAGE.
Endotoxin
<0.1 EU per 1 μg of the protein by the LAL method.
Bioactivity
Measure by its ability to induce hemoglobin expression in K562 cells. The ED50 for this effect is <1 ng/mL.
Form
Reconstitution
Molecular Weight
The protein has a calculated MW of 13.71 kDa. The protein migrates about 17 kDa under reducing condition (SDS-PAGE analysis) .
Storage Conditions
AA Sequence
Frequently Asked Questions
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