Mouse recombinant Noggin protein, AF
Noggin binds members of the transforming Growth Factors-beta (TGF beta) superfamily signaling proteins, such as bone morphogenetic protein-4 (BMP-4), which inactivates their activities. As a extracellular antagonist of BMP proteins, Noggin involves in the development of many body tissues, including nerve tissue, muscles, and bones. In addition, Noggin is able to inhibit chondrocyte differentiation through its interaction with GDF5.
Product Specifications
Synonyms
Nog
Gene Name
NOG
UniProt
P97466
Reactivity
Mouse
Tag
Human IgG1 Fc Tag (C-term)
Source
HEK293 cell
Applications
Cell Culture
Purification
>95% as determined by SDS-PAGE.
Endotoxin
<0.1 EU per 1 μg of the protein by the LAL method.
Bioactivity
Testing in process
Form
Reconstitution
Molecular Weight
The protein has a calculated MW of 49.14 kDa. The protein migrates as 50 kDa under reducing condition (SDS-PAGE analysis) .
Storage Conditions
AA Sequence
A DNA sequence encoding Mouse Noggin (#P97466) (Met1-Cys232) was expressed with Human IgG1 Fc tag at the C-terminus.
Frequently Asked Questions
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