Human recombinant IL-2 protein, GMP
Interleukin-2 (IL-2) is a 15.5 kDa four bundle, immuno-modulatory cytokine which is expressed predominately by antigen-simulated CD4+ T cells, CD8+ T cells, natural killer (NK) cells, and dendritic cells (DC) . IL-2 plays a fundamental role in promoting NK cell proliferation, cytotoxicity, and B cells differentiation. IL-2 modulate T cell differentiation programs, promoting naïve CD4+ T cell differentiation into T helper-1 (Th1) and T helper-2 (Th2) cells.
Product Specifications
Synonyms
T-cell Growth Factor (TCGF), Aldesleukin
Gene Name
IL2
UniProt
P60568
Reactivity
Human
Tag
His Tag (C-term)
Source
Escherichia coli
Applications
Cell culture, ELISA
Purification
>98% as determined by SDS-PAGE analysis.
Endotoxin
<0.05 EU per 1 μg of the protein by the LAL method.
Bioactivity
Form
Lyophilized from a 0.2 μm filtered solution of PBS, pH 8.0.
Reconstitution
Molecular Weight
The protein has a calculated MW of 16.4 kDa. The protein migrates as 13 kDa under reducing condition (SDS-PAGE analysis) .
Storage Conditions
AA Sequence
Frequently Asked Questions
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