Human recombinant CXCL12 (24-88) (C-X-C motif chemokine 12) protein, AF
C-X-C motif chemokine 12 (CXCL12) also named stromal cell-derived factor 1 (SDF-1), which is a chemokine of the intercrine alpha family. CXCL12 is a 19.5kDa protein containing 167 amino acid residues. The function of CXCL12 include the hematopoiesis, angiogenesis embryogenesis, inflammation and angiogenesis. CXCL12 activated by the IL-1, TNF or lipopolysaccharide and induce the immune response in leukocytes.
Product Specifications
Synonyms
IRH, PBSF, SCYB12, SDF1, TLSF, TPAR1
Gene Name
CXCL12
UniProt
P48061
Reactivity
Human
Tag
His Tag (C-term)
Source
Escherichia coli
Applications
Cell Culture
Purification
>98% as determined by SDS-PAGE.
Endotoxin
<0.1 EU per 1 μg of the protein by the LAL method.
Bioactivity
Measure by its ability to chemoattract BaF3 cells transfected with human CXCR4. The ED50 for this effect is <0.5 ng/mL.
Form
Reconstitution
Molecular Weight
The protein has a calculated MW of 8.55 kDa. The protein migrates as 10 kDa under reducing condition (SDS-PAGE analysis) .
Storage Conditions
AA Sequence
MVSLSYRCPCRFFESHVARANVKHLKILNTPNCALQIVARLKNNNRQVCIDPKLKWIQEYLEKALN with polyhistidine tag at the C-terminus.
Frequently Asked Questions
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