Human recombinant BMP-6 (Bone morphogenetic protein-6) protein, AF
Bone Morphogenetic Protein-6 (BMP-6) is an extracellular multifunctional cytokine that is also a member of the TGF-β family. BMP-6 can bind with the TGF-β receptor and triggers SMAD protein signal transduction. It can keep joint integrity and stability in adults and plays a vital role in regulating hepcidin to maintain iron ions in the body.
Product Specifications
Synonyms
VGR, VG-1-related protein
Gene Name
BMP6
UniProt
P22004
Reactivity
Human
Tag
His Tag (C-term)
Source
Escherichia coli
Applications
Cell Culture
Purification
>98% as determined by SDS-PAGE.
Endotoxin
<0.1 EU per 1 μg of the protein by the LAL method.
Bioactivity
Measure by its ability to induce alkaline phosphatase production by ATDC5 cells. The ED50 for this effect is <87 ng/mL.
Form
Reconstitution
Molecular Weight
The protein has a calculated MW of 14.07 kDa. The protein migrates as 13 kDa under reducing condition (SDS-PAGE analysis) .
Storage Conditions
AA Sequence
Frequently Asked Questions
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