Human recombinant VEGF121 (Vascular endothelial growth factor 121) protein, AF
Vascular Endothelial Growth Factors 121 (VEGF121) is one of five VEGF splice variants of 121, 145, 165, 183, 189, and 206 amino acids (aa) in length. VEGF121 is the only VEGF which lacks heparin-binding activity and freely diffusible. VEGF binds the type I transmembrane receptor tyrosine kinases VEGF R1 (also called Flt-1) and VEGF R2 (Flk-1 /KDR) on endothelial cells to activate signal transduction and regulate both physiological and pathological angiogenesis.
Product Specifications
Synonyms
VPF
Gene Name
VEGFA
UniProt
P15692
Reactivity
Human
Tag
His Tag (C-term)
Source
Escherichia coli
Applications
Cell Culture
Purification
>95% as determined by SDS-PAGE.
Endotoxin
<0.1 EU per 1 μg of the protein by the LAL method.
Bioactivity
Measure by its ability to induce proliferation in HUVEC cells. The ED50 for this effect is <2.5 ng/mL.
Form
Reconstitution
Molecular Weight
The protein has a calculated MW of 15.00 kDa. The protein migrates as 18 kDa under reducing condition (SDS-PAGE analysis) .
Storage Conditions
Product Datasheet
https://www.bosterbio.com/datasheet?sku=PROTP15692-17
AA Sequence
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
Lentiviral mouse Gabrg3 shRNA (UAS) - Lentiviral mouse Gabrg3 shRNA (UAS, GFP) (100)
Recombinant Cupriavidus necator Aspartate--tRNA ligase (aspS), partial